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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12009 | Telomerase-IN-1 | Telomerase | |
Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER overreaction (EOR), which then induces ERS, leading to apopto... | |||
T13174 | TMPyP4 tosylate | TMP 1363 | DNA/RNA Synthesis , Telomerase |
TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines. | |||
TN1059 | Ganoderic acid B | IL Receptor , HIV Protease , JAK , STAT | |
Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has an... | |||
T2988 | (-)-Epigallocatechin Gallate | Epigallocatechol Gallate,EGCG | Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy |
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor... | |||
T72789 | Telomerase-IN-4 | Apoptosis | |
Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1]. | |||
T72790 | Telomerase-IN-5 | Apoptosis | |
Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1]. | |||
T61679 | Abacavir monosulfate | ||
Abacavir monosulfate is an orally active, competitive nucleoside reverse transcriptase inhibitor that effectively inhibits HIV replication. Additionally, it exhibits anticancer properties in prostate cancer cell lines, a... | |||
T35428 | β-Rubromycin | ||
β-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 μM, ... |